Avène RetrinAL Day crème targets wrinkles and loss of firmness. This day cream's patented combination of Collactin, Pre-Tocopheryl, and Hyaluronic Acid MO, works to rejuvenate dry, sensitive skin. Its hypoallergenic, non-comedogenic formula provides moisture while addressing visible signs of aging. Avène RetrinAL helps to restore a youthful and radiant complexion.